AstraNova's phenotypic biology team operates some of the most sophisticated cellular model systems available to the CRO sector, enabling compound assessment in contexts that genuinely predict translational outcomes.
Our biology team can help select 2D, 3D, organoid, co-culture, or immune models that match the translational question your program needs answered.
Multi-parametric cellular imaging capturing morphological, functional, and molecular readouts simultaneously. Our Opera Phenix and ImageXpress Micro platforms support up to 384-well format with automated image analysis and AI-assisted feature extraction.
Physiologically relevant three-dimensional tumor models that better recapitulate the biology of solid tumors compared to traditional 2D cultures. Our validated spheroid library spans 25+ cancer cell line origins with tiered complexity options.
Complex co-culture systems modeling tumor-immune interactions, stromal contributions, and tissue microenvironments. Essential for immune-oncology programs requiring in vitro mechanistic validation before animal studies.
Full-service phenotypic screening campaigns using physiologically relevant model systems, followed by target deconvolution strategies to transform phenotypic hits into mechanistically understood lead series.
Bring us the program question, constraints, and next decision point. We will map the right assays, controls, timeline, and reporting package before the first plate is run.
